MUSC HealthPlex | Fitness offers health, fitness and wellness services in Orangeburg, SC. MUSC HealthPlex is a multi-site fitness and wellness center. With 5 locations, we serve the residents of Orangeburg, St. Matthews, Holy Hill, Branchville, Santee and neighboring communities. NOTE: We are open 24/7 for active fitness members; however if you are looking to join MUSC HealthPlex as a new member please call to schedule a time to visit us during staffed hours, which are limited. Thank you!