Wyoming Valley Health Care System was founded in 1992 with the merger of two of the region's oldest and most respected health care institutions: Nesbitt Memorial Hospital and Wilkes-Barre General Hospital. Since that time, it has continued to grow and evolve to provide the most comprehensive health care in Northeastern Pennsylvania.

In the fall of 2001, all acute care services at Nesbitt Memorial Hospital were transferred to and consolidated at Wilkes-Barre General Hospital - making it the region's largest and finest acute care hospital. Following extensive renovations, Nesbitt Memorial Hospital was renamed Nesbitt Memorial Medical Center and the majority of our behavioral health services relocated into the reconstructed facility in the summer of 2002.

In addition to Wilkes-Barre General Hospital, Wyoming Valley Health Care System also includes our affiliates:
- Behavioral Health Services of Wyoming Valley - including inpatient and outpatient mental health care and substance abuse services for children, adolescents and adults.
- Heritage House and Wyoming Valley Manor - offering retirement, long-term care and hospice care facilities for patients or seniors.
- United Health and Hospital Services (UHHS) - providing primary and obstetric care to the under-served of our community. UHHS also offers the Wyoming Valley Family Practice Residency Program, which provides practical and educational training to student physicians.
- Visiting Nurse Association - providing in-home nursing, personal and hospice care to residents throughout Luzerne and surrounding counties.